Organophosphorus ester-induced chronic neurotoxicity

Organophosphorus compounds have three distinct neurotoxic actions.

The primary action is the irreversible inhibition of acetylcholinesterase, resulting in the accumulation of acetylcholine and subsequent over-stimulation of the nicotinic and muscarinic acetylcholine receptors leading to cholinergic effects…

Read more here: Abou-Donia-Organophosphorus-ester-induced-chronic-neurotoxicity

RUTH MEDINA v NORTHWEST AIRLINES [2005]

Upon arrival in San Francisco on December 13, 2000, the Applicant had eye irritation, chest tightness, and chest pain, consistent with exposure to ozone gas. She also had nausea, headache, and fatigue consistent with the initial effects of exposure to components of aerosolized Exxon 2380, the engine oil that NWA was using on its 747-200…