Organophosphorus ester-induced chronic neurotoxicity

Organophosphorus compounds have three distinct neurotoxic actions.

The primary action is the irreversible inhibition of acetylcholinesterase, resulting in the accumulation of acetylcholine and subsequent over-stimulation of the nicotinic and muscarinic acetylcholine receptors leading to cholinergic effects…

Read more here: Abou-Donia-Organophosphorus-ester-induced-chronic-neurotoxicity