Tricresyl phosphate and the aerotoxic syndrome of flight crew members – Current gaps in knowledge

Abstract Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other…

Quantifying Exposure to Pesticides on Commercial Aircraft – ACER

Assessment of potential health risks to flight attendants from exposure to pyrethroid insecticides, used for aircraft disinsection, is limited because of (a) lack of information on exposures to these insecticides, and (b) lack of tools for linking these exposures to biomarker data. We developed and evaluated a physiologically based pharmacokinetic (PBPK) model to assess the…

Proposed Test Plans for a Study of Bleed Air Quality in Commercial Airliners


The Airliner Cabin Environment Research (ACER) Program of the National Air Transportation Center of Excellence for Research in the Intermodal Transport Environment (RITE) has developed two research plans for an extensive study of bleed air incidents on aircraft operating in the United States.

Read the full report: Proposed Test Plans – Section 320