Organophosphate Poisoning – Patient.co.uk

The organophosphate (OP) pesticides inhibit acetylcholinesterase. Hence acetylcholine accumulates at nerve synapses and neuromuscular junctions, stimulating muscarinic and nicotinic receptors and the central nervous system.They are used as pesticides but can also be used as ‘nerve gas’. This is prohibited under the Geneva Convention but could be used by terrorists or rogue regimes. Read the…

Autoantibody markers of neural degeneration are associated with post-mortem histopathological alterations of a neurologically-injured pilot

ABSTRACT. There are numerous concerns regarding the neurotoxicity of contaminated air inside pressurized aircraft. Neurological symptoms have been seen in many aircrew personnel who have reportedly been exposed to the potentially toxic breathable air in airliners. Symptoms, allegedly contracted by aircrew and passengers, are thought to be caused by a single large exposure or repetitive…

Tricresyl phosphate and the aerotoxic syndrome of flight crew members – Current gaps in knowledge

Abstract Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other…

Quantifying Exposure to Pesticides on Commercial Aircraft – ACER

Assessment of potential health risks to flight attendants from exposure to pyrethroid insecticides, used for aircraft disinsection, is limited because of (a) lack of information on exposures to these insecticides, and (b) lack of tools for linking these exposures to biomarker data. We developed and evaluated a physiologically based pharmacokinetic (PBPK) model to assess the…

Proposed Test Plans for a Study of Bleed Air Quality in Commercial Airliners

Abstract

The Airliner Cabin Environment Research (ACER) Program of the National Air Transportation Center of Excellence for Research in the Intermodal Transport Environment (RITE) has developed two research plans for an extensive study of bleed air incidents on aircraft operating in the United States.

Read the full report: Proposed Test Plans – Section 320

[German] Aerotoxic syndrome: basic, pathophysiology and therapy with the therapeutic apheresis

abstract Aerotoxic syndrome: Background, Pathophysiology, and treatment with therapeutic apheresis This work will form the basis of the detailed Aerotoxic syndrome, the pathophysiological consequences and modern treatment options. At the same time attention is drawn to the fact that the Aerotoxic Syndrome, as we know it is due to a design flaw of all aircraft…