Organophosphorus ester-induced chronic neurotoxicity

Organophosphorus compounds have three distinct neurotoxic actions.

The primary action is the irreversible inhibition of acetylcholinesterase, resulting in the accumulation of acetylcholine and subsequent over-stimulation of the nicotinic and muscarinic acetylcholine receptors leading to cholinergic effects…

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Corporate affiliation bias and BAe 146 aircraft: (Australian) Senate report

The Australian Senate has completed an inquiry into aircraft air quality in the BAe 146 aircraft because of many incidents of apparent toxic illness among the crew. The Senate Committee concluded that cabin contamination continues to occur(1) and that this has led to short-term and medium-term health problems for a number of BAe 146 flight…

Air Safety and Cabin Air Quality in the BAe 146 Aircraft – Report by the Senate Rural and Regional Affairs and Transport References Committee (Australia)

The Senate Rural & Regional Affairs & Transport References Committee commenced an inquiry on a range of airspace and air safety issues in early 1999. The Committee was aware at the time it started its inquiry that there had been a history of complaints concerning the quality and effects of cabin air quality in the…

AEROTOXIC SYNDROME: ADVERSE HEALTH EFFECTS FOLLOWING EXPOSURE TO JET OIL MIST DURING COMMERCIAL FLIGHTS

Abstract Materials used in the operation of aircraft may contain hazardous ingredients, some with significant toxicities, and need care in handling and use. Some maintenance or operational activities, such as leaks or poorly controlled maintenance procedures, can, through contamination of aircraft cabin air, produce unwanted exposures to personnel and passengers. Occasionally, such exposures (either short…

Medical Aspects of work-related exposures to organophosphates – Guidance Note MS17 – Health and Safety Executive

Guidance Note MS17 INTRODUCTION The purpose of this guidance note is to inform doctors and other health professionals, particularly those concerned with occupational health, about the health effects which may arise from exposure to organophosphates and the role of biological monitoring and health surveillance of workers expsed to these compounds. Organophosphates (OPs) are a broad…